This article via: Researchers to make better and cheaper anti-chip
Researchers to make better and cheaper anti-chip
The medical "micro laboratory" of Brigham Young University is like a coin sorters. It can detect the smallest virus concentrations. The production costs are lower than for comparable chips.
A development team of Brigham Young University (BYU) has developed a medical laboratory viruses, which has a micro chip. It should be not only small and recognize certain viruses and proteins reliably even in very small concentrations, it is still relatively cheap fujitsu lifebook t4220 battery.
The invention, which is presented in the journal "Lab on a Chip" works like a microscopic M¨¹nzsortierautomat. Fluids on the chip run, hitting a wall, is located in a slot. This slot is smaller than the tiny particles, which one would look for. The desired particle pile up therefore before the wall where you can see them with a special camera.
Through this technique, it does not matter how big the sample being studied or the concentration of the desired virus. It's all about the size of the particles, not their number. This is according to the researchers, allow for much earlier detection of viruses.
"Most of the tests that you get to the hand, are quite inaccurate, if one finds not just a really high concentration of a virus," says Aaron Hawkins, a professor of electrical and computer engineering at BYU and director of chip development. "One of the goals of the" Chip-Labor "community to also be able to measure individual particles that flow through a tube or a channel."
The cost for a small and sufficiently sensitive chip with nano-components are usually in the millions. The BYU group aims to cut costs by using a simpler machine that they first form a two-dimensional form in the micrometer range. This dimension is a thousand times larger than the nanometer range. Then a 50 nm thin metal layer applied to the chip and a glass layer, which is placed with the help of gases. An acid wash and then the metal of the chip, making the slots occur in the glass, in which the viruses are caught later.
Hawkins said his team will now proceed to produce chips with multiple, ever narrowing slits. They could be in a same sample and look for particles of different sizes. It should be pretty easy to identify which proteins or viral contamination. One must look only in front of what slots would have jammed particles.
According to the researchers, their chip can be useful not only in the detection of viruses and proteins. David Belnap, chemistry professor and co-author of the report, says that a chip like that of the BYU accelerate the research. The mini-lab can also supply high-purity samples namely, how they are necessary for the study of viruses and virus behavior.
BYU professor Aaron Hawkins keeps the virus lab-on-a-chip in the fingers (Image: Mark A. Philbrick, Brigham Young University).
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